1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
When there are several drugs on different therapeutic doses (or in some cases, combination therapy), the treating physician can mix and replace the drugs, or selected drugs may become replacements, that are ineffective or negatively interaction with each other.There are, however, several drugs that can all be used to treat erectile dysfunction (ED) and they areAUD (Alcohol, Drug-Alcohol Interaction). These drugs, although used to help manage erectile dysfunction, can still cause side effects including:
Refraining from combining these medications with drugs on different therapeutic doses can significantly improve outcomes for patients with ED.
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Erection problems (impotence) are very common, particularly in men over 40.
Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.
If it happens more often, it may be caused by physical or emotional problems.
Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.
Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety
Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.
If you experience any of the following side effects stop using the medicine and seek medical help immediately:
allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:
Common (seen in 1 to 10 in every 100 patients)
headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)
dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)
fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.
Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.
Herrera W. S. Al-Guayas
Qiao-Jun Hun Cui Cui Jins Hui Guo Yuhai Bai Jun Cai Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun47 medicines classificationThe maximum allowed therapeutic dose of CIALIS is 40 mg.
48 medicines class I granted classificationThe FDA has approved the first generic version of Tadalafil for the treatment of erectile dysfunction (ED) in men. The drug is approved in the United States and Europe for the treatment of ED in men over 40.
Erectile dysfunction (ED) is a common condition that affects approximately 30 million men in the United States. It is characterized by the inability to achieve or maintain a hard, erect penis suitable for sexual activity. The condition can lead to reduced sexual satisfaction, relationship satisfaction, and overall quality of life.
ED can be treated with a variety of medications including a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. These drugs work by increasing blood flow to the penis during sexual stimulation, allowing for an erection.
For the treatment of ED, men can take Tadalafil 5 mg and Cialis 5 mg as needed, daily. They can be taken as needed, up to 36 hours after a meal. Tadalafil 5 mg can also be taken with food, although it is recommended to take it with a meal to reduce the risk of stomach upset. For men over the age of 18, Tadalafil 5 mg is the standard treatment for ED.
Both Cialis and Tadalafil are effective in treating ED symptoms. However, they differ in their side effects. Tadalafil 5 mg can cause more serious side effects such as headache, muscle aches, and flushing. These side effects tend to be more common in men taking higher doses of the drug, and in those who experience more severe side effects.
In addition to the above, Tadalafil 5 mg can also cause dizziness and lightheadedness in some men. If you experience any of these side effects, call your doctor immediately or go to the emergency room.
In rare cases, tadalafil can cause serious side effects in rare cases. This is due to the long half-life of the drug in the body, which can lead to low blood pressure, dehydration, and electrolyte imbalances. Tadalafil 5 mg should be used under medical supervision.
Tadalafil can be taken with or without food, but it can be taken with or without water. This allows the medicine to work more effectively in the body, helping to relax the muscles and improve blood flow.
If you are taking a medication that may cause side effects, speak to your doctor about alternatives to Tadalafil. They may recommend switching to another ED medication or adjusting the dosage if needed.
In conclusion, tadalafil 5 mg and Cialis 5 mg are effective treatment options for erectile dysfunction in men. However, they are not suitable for everyone, and it may not be suitable for everyone.